Mal Wheeler's practice focuses on large and complex business litigation and product liability litigation, especially nationwide "pattern" litigation, class actions, and major appeals. He has defended manufacturers at trial in several highly publicized cases, including the Pinto criminal prosecution, the Kearns windshield-wiper patent case, the first "no airbag" case tried to verdict, the first defective airbag case tried to verdict, and cases in the medical device, pharmaceutical, chemical, automotive, and appliance industries.  He has briefed and argued cases in the United States Supreme Court, in United States Courts of Appeals, and in state appellate courts throughout the country.

Mr. Wheeler has been the designated media representative for several Fortune 500 companies in connection with major litigation.  In that role, he has appeared on nationally broadcast television programs, including ABC's 20/20, CNN's Burden of Proof, Dateline NBC, and 90 Minutes (a European news show), as well as nationally broadcast radio programs.